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BestsellerRxWeekly weight loss injection

Wegovy

Wegovy

21%
avg weight loss over a 72-week period*

A prescription-only medication that effectively targets weight loss. Used weekly, the active ingredient in Wegovy (semaglutide) mimics the hormone GLP-1** and works by reducing cravings and helping you feel fuller for longer.

Pay as you go. Promo and discount codes can be added at checkout

Your weight-loss pathway with Curate

  • Check your eligibility for weight-loss medication with a quick online consultation.
  • If eligible, book a short video call to ask questions and explore options.
  • Once approved, your personalised pathway is individually designed by a clinician.
  • Your medication is delivered, discreetly packaged. .
  • You’re never alone with specialist one-to-one support throughout your journey.
  • Whole-person healthcare with nutrition, exercise and wellbeing advice.
  • Tailored supplements to work with your changing needs. 
  • Measure your progress and stay on track through your own dashboard.

How Wegovy works

The active ingredient in Wegovy (semaglutide) mimics the gut hormone GLP-1. Here’s how it works:

GLP-1 is the hormone released after eating. Wegovy activates the GLP-1 receptor, slowing down stomach emptying to help you feel fuller for longer. It also boosts insulin release to regulate blood sugar levels, and the brain is cleverly alerted to reduce appetite and limit cravings. 

This makes Wegovy a highly effective weight-loss medication. Use alongside your curated treatment pathway for lasting change.

How to use Wegovy

Dose and frequency 

Using Wegovy is simple. Your injection pen is pre-filled with four doses, taken once a week (on the same day), using a new needle each time. To help your body adjust to the medication, we start with a low dose which gradually increases over time until you reach your maximum amount. It’s different for everyone, and your clinician will work with you to find your sweet spot. This method reduces potential side effects and increases effectiveness for lasting results. 

Where to inject

Wegovy is injected into fatty tissue (not your vein). Choose the area most comfortable for you:

Stomach - At least 2 inches/5cm (no closer) away from your belly button. Many choose this as it’s easy to reach.

Either thigh - The front upper part, avoiding your inner thigh.

Upper arm: The back, outer area. This is tricky to reach, so you may need someone to help you.

Rotate the exact spot each week to avoid irritation. Avoid bruised, tender, sore or sunburnt skin, as well as scar tissue, moles, birthmarks, tattoos and varicose veins. 

STEP-BY-STEP GUIDE 

You'll need

  • Your Wegovy pen
  • New needle
  • Sharps bin

Get prepared

  • Wash hands thoroughly. 
  • Check the pen is in date and undamaged. The liquid should be clear and colourless.
  • Let the pen come to room temperature for 15 minutes if it’s been stored in the fridge. It’ll feel more comfortable. 
  • Take off the pen cap.
  • Always attach a new needle by removing the paper tab, pushing the needle onto the pen and twisting until secure.
  • Remove both outer and inner needle caps (keeping the outer cap for later).

Check the flow

  • Turn the dose selector until the flow check symbol appears.
  • Hold the pen with the needle pointing up.
  • Press and hold the dose button until a ‘0’ appears on the dose counter.
  • A drop of medication should appear at the needle tip, and your pen is ready to use.
  • You only need to check the flow once with a new pen (not in the 3 weeks when you change the needle).

You’re ready to inject

  • Turn the dose selector until your prescribed dose appears.
  • Push the needle directly into your skin.
  • Press and hold the dose button until a ‘0’ on the dose counter.
  • Continue pressing for at least 6 seconds to complete the dose.
  • Carefully remove the needle from your skin

After injecting

  • You may see a small drop of blood, which is normal. 
  • Gently press and hold with a cotton pad or tissue. Do not rub.
  • Place the outer needle cap back on, unscrew and dispose of the needle in a sharps bin.
  • Replace the pen cap and store following the storage instructions. 

Potential common side effects

Wegovy is generally well-suited to most people. Common side effects are with the digestive system. They’re usually experienced at the start of treatment or when increasing the dose.

Most common side effects (may affect over 1 in 10 people):

  • Headache
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Bloating
  • Stomach discomfort
  • Fatigue

Your clinician will run through all side effects with you and discuss any concerns you may have.

Actual price will depend on pay as you go or subscription plan purchase, promotional offers and discount codes are available to input at checkout. Requires an online consultation with a clinician who will determine if treatment is appropriate.


*Wharton S, et al. Once-weekly semaglutide 7.2 mg in adults with obesity (STEP UP): a randomised, controlled, phase 3b trial. The Lancet Diabetes & Endocrinology. 2025;13(11):949–963. This trial was for Wegovy over 72 weeks. Average weight loss: up to 20.7% in STEP UP trials.

**Glucagon-like peptide (GLP-1)

View full details

Start your journey In 3 simple steps

Complete your online consultation

Let’s get to know you. Simply fill in our online questionnaire to check your eligibility for medication.

Get reviewed by a clinician 

One of our specialised clinicians will review your consultation. If approved, your personalised treatment pathway will be created.

Start your treatment 

Treatment delivered and you’re ready to go. Don’t worry, our packaging is discreet. This is your journey, no one else’s.

A new routine for a whole new you 

Week 1

Let’s go

  • Choose a day to use your weekly injection and off you go.
  • You may notice a reduced appetite within the first few days.
  • A little nausea or bloating is common as your body adjusts.
Week 2

Get settled

  • Use your second injection, on the same day, a week later.
  • A reduced appetite should become more consistent.
  • Get into a routine with your nutrition plan. And stay hydrated.
Week 3

Consistency is key

  • Use your third weekly injection exactly a week later.
  • Your energy levels and appetite should feel regulated.
  • Order your next monthly dose of Wegovy to stay on track. 
Week 4

Month 1 complete

  • Time for your last weekly injection of the month.
  • Record appetite and weight changes on your dashboard.
  • Check in with a clinician for a dose adjustment, if needed.

Let me know how I can help

I hope your first week goes well

  • Sustained Energy
  • Metabolic Balance
  • Reduced Cravings
  • Improved Confidence
  • Healthier Body Composition

Questions? We’re here to help.

Is Wegovy safe? 

Wegovy has been extensively studied and is licensed in the UK for effective weight management in adults. It is approved by NICE (the National Institute for Health and Care Excellence) and is one of the most clinically researched weight-loss medications available. 

As with all medications, it isn't suitable for everyone — which is why every Curate prescription follows a thorough clinical assessment. The most commonly reported side effects are gastrointestinal — including nausea and digestive discomfort — and tend to settle as your body adjusts. Your clinician will review your full health history before prescribing and will support you throughout your treatment.

How long does Wegovy take to work? 

Most people begin to notice a difference in appetite and food cravings within the first few weeks of starting Wegovy. Weight-loss changes typically become visible between four and eight weeks, with more significant results building over three to six months. 

Wegovy is introduced gradually — starting at a lower dose and increasing over sixteen to twenty weeks — to allow your body to adjust and minimise side effects. The results build with consistency over time, and your clinician will support you through every stage of that process.

What is the difference between Wegovy and Mounjaro ? 

Both are clinically proven weight-loss medications that are injected weekly. But they work differently. Wegovy contains semaglutide, which mimics the single hormone glucagon-like peptide (GLP-1) to reduce cravings and help you feel fuller for longer. Mounjaro contains tirzepatide, which targets the two hormones GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) simultaneously to slow digestion, reduce appetite and help you feel fuller for longer. 

Individual results vary with both medications. The right choice depends on your health history, your body and your goals. And that’s what we’re here for. Your clinician will assess this during your consultation to find the most effective medication for you.